Poroshell

Poroshell Chiral Columns from Agilent Technologies

Agilent InfinityLab Poroshell 120 Chiral columns offer chiral stationary phases on rugged, dependable, superficially porous Poroshell 120 particles. Take advantage of the performance and speed benefits of superficially porous particles to increase your productivity with fast, efficient, high resolution chiral separations. Available in four different chiral chemistries across four different LC modes these columns offer a wide range of selectivities to separate enantiomers of nearly any chiral compound.

Poroshell

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Features
  • Boost the efficiency of chiral separations with chiral phases on 2.7 µm superficially porous Poroshell 120 particles
  • Superior peak shape, resolution, and analysis speed with high efficiency separations
  • Increase throughput and productivity with fast run times
  • Rugged and reliable performance on Agilent’s proven Poroshell 120 particle technology
  • 2.1 and 4.6 mm id configurations in 50, 100, and 150 mm lengths
  • Choose from four different chiral chemistries that cover separations for a wide range of analytes
  • Explore the four different LC modes (polar organic, polar ionic, reversed-phase, and normal phase) to obtain the optimal separation conditions
Specifications
Column Chemistry Chiral Selector Pressure Limit pH Range Temp Limit Common Mode Common Applications
Poroshell 120 Chiral-CF Derivatized cyclofructan (CF6) 400 bar 3 - 7 45 °C Polar Organic (PO) Primary amines
Normal Phase (NP) Primary amines
Poroshell 120 Chiral-CD Hydroxypropylated-β-cyclodextrin 400 bar 3 - 7 45 °C Reversed Phase (RP) Stimulants, fungicides, t-boc amino acids
Polar Organic (PO) Complex molecules
Poroshell 120 Chiral-V Vancomycin (macrolide antibiotic) 400 bar 2.5 - 7 45 °C Polar Ionic (PI) Basic pharmaceuticals (various)
Reversed Phase (RP) Amines, profens
Polar Organic (PO) Complex neutral molecules
Poroshell 120 Chiral-T Teicoplanin (macrolide antibiotic) 400 bar 2.5 - 7 45 °C Polar Ionic (PI) Beta blockers, hydroxyl acids
Reversed Phase (RP) Amino acids, hydroxyl acids, profens
Polar Organic (PO) Hydantoins, benzodiazepines
Literature